ChatGPT-4o versus Gynecologic Oncologists in Endometrial Cancer Patient Communication: A Prospective Comparative Study

Study Background and Disease Burden

Endometrial cancer represents one of the most common gynecologic malignancies worldwide, with increasing incidence attributed to aging populations and rising obesity rates. Effective patient communication regarding risk factors, preventive strategies, diagnostic procedures, and treatment options is essential to optimize patient outcomes and quality of life. However, time constraints in clinical encounters and variability in communication skills may limit thorough patient education. This unmet need presents an opportunity to explore artificial intelligence (AI) applications like ChatGPT-4o to supplement clinical interactions and improve patient understanding and support. By examining AI performance against specialized gynecologic oncologists in addressing patient inquiries about endometrial cancer, this study provides timely insights into AI’s role within the evolving oncology care landscape.

Study Design

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