Highlights
Isolated severe systolic hypertension (ISSH), defined as a systolic blood pressure (SBP) ≥160 mmHg with a diastolic blood pressure (DBP) <110 mmHg, is a significant and independent risk factor for severe maternal morbidity.
In a secondary analysis of the APEX cohort, patients with SBP between 160-179 mmHg faced a 2.8-fold increase in adverse maternal outcomes, while those with SBP ≥180 mmHg faced a nearly 4-fold increase compared to patients with mild hypertension.
