Highlight
- Reduction mammoplasty carries a 26% risk of wound-healing complications within 30 days postoperatively.
- The 5-factor modified frailty index (mFI-5) showed limited predictive value for wound-healing complications after breast reduction surgery.
- Advanced patient age, particularly over 51 years, independently predicted increased wound-healing complications.
- Age remains a critical factor for patient counseling and surgical risk stratification beyond conventional frailty metrics.
