AI-Assisted Line-Field Confocal Optical Coherence Tomography for Early Detection of Subclinical Basal Cell Carcinoma: Current Evidence and Clinical Prospects

Basal cell carcinoma (BCC) is the most frequent skin cancer, with early detection critical to reduce morbidity from facial lesions.
Line-field confocal optical coherence tomography (LC-OCT) provides high-resolution, noninvasive imaging of skin architecture, enabling detection beyond visible lesions.
Artificial intelligence (AI) integration with LC-OCT enhances diagnostic accuracy for subclinical BCC in high-risk populations, with positive predictive values up to 94.4%.
Subtype classification of BCC via AI-assisted LC-OCT shows promising accuracy, aiding tailored clinical management.