Telephone-Based Weight Loss Intervention Enhances Outcomes in Women With Stage II/III Breast Cancer: Insights From the BWEL Trial and Complementary Studies

Highlights

• Telephone-based weight loss intervention (WLI) yields significant 1-year weight reduction in women with stage II/III HER2-negative breast cancer and BMI ≥27.
• Intervention effective across racial and ethnic subgroups, with greater weight loss in postmenopausal and non-Black/non-Hispanic women.
• Weight loss correlates with adherence to coaching calls, emphasizing the importance of engagement.
• Prior randomized trials suggest telephone counseling is a feasible alternative to in-person sessions, with favorable outcomes on body composition and inflammation markers.

Background