Association of Common Ancestry-Enriched Variants With Cardiomyopathy and Arrhythmias: Insights From Genetic Studies in Individuals of African Ancestry

Association of Common Ancestry-Enriched Variants With Cardiomyopathy and Arrhythmias: Insights From Genetic Studies in Individuals of African Ancestry

Genetic variants enriched in individuals of African ancestry confer increased risk of cardiomyopathy and arrhythmias, with cardiovascular risk factors amplifying this risk. Large biobank studies enable reclassification of key variants and highlight the need for ancestry-specific genetic risk assessment.