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Upadacitinib and Janus Kinase Inhibitors in Giant-Cell Arteritis: Clinical Trial and Real-World Evidence
Posted inClinical Updates news Rheumatology Specialties

Upadacitinib and Janus Kinase Inhibitors in Giant-Cell Arteritis: Clinical Trial and Real-World Evidence

Posted by By MedXY 08/02/2025
Upadacitinib at 15 mg with a 26-week glucocorticoid taper shows superior efficacy and comparable safety to placebo in giant-cell arteritis. Real-world data suggest JAK inhibitors, including upadacitinib, may benefit relapsing cases unresponsive to conventional therapies.
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Rituximab Shows No Superiority Over Conventional Therapy for EGPA Remission Induction
Posted inClinical Updates news Rheumatology Specialties

Rituximab Shows No Superiority Over Conventional Therapy for EGPA Remission Induction

Posted by By MedXY 07/31/2025
A phase 3 randomized trial found rituximab no more effective than standard glucocorticoid-based therapy in inducing remission in eosinophilic granulomatosis with polyangiitis (EGPA), with comparable safety and relapse profiles.
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