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transcriptional regulation

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USP22：KMT2A重排急性白血病的新治疗脆弱点——调控MEIS1稳定性与致癌转录
Posted inClinical Updates Hematology-Oncology

USP22 as a Therapeutic Vulnerability in KMT2A-Rearranged Acute Leukemia: Regulating MEIS1 Stability and Oncogenic Transcription

Posted by By MedXY 11/11/2026
Recent evidence identifies USP22 as a key regulator of MEIS1 protein stability, revealing a promising therapeutic target to disrupt leukemogenic transcription in KMT2Ar acute leukemia.
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