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Posted innews Oncology

Biomarker-Driven Precision in Low-Grade Serous Ovarian Cancer: pERK and MAPK Mutations as Predictors of Trametinib Efficacy

Posted by Zhang Paul By Zhang Paul 01/12/2026
Highlights High tumour pERK expression (histoscore >140) is a significant predictor of prolonged progression-free survival…
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Posted inClinical Updates news Oncology

Targeting the MEK/RTK Axis: A Promising Combination Therapy for KRAS-Mutant Non-Small Cell Lung Cancer

Posted by MedXY By MedXY 09/19/2025
Combining MEK inhibitor trametinib with pan-RTK inhibitor anlotinib shows high efficacy and manageable toxicity in treating advanced non-G12C KRAS-mutant NSCLC, overcoming adaptive resistance and offering improved clinical outcomes.
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