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T cell exhaustion

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Linperlisib Potentiates MUC1-Tn CAR T Cell Therapy by Suppressing the EGR1/DUSP2 Axis to Combat T-Cell Acute Lymphoblastic Leukemia
Posted inHematology-Oncology news

Linperlisib Potentiates MUC1-Tn CAR T Cell Therapy by Suppressing the EGR1/DUSP2 Axis to Combat T-Cell Acute Lymphoblastic Leukemia

Posted by MedXY By MedXY 07/06/2026
This study highlights how linperlisib, a PI3Kδ inhibitor, enhances MUC1-Tn CAR T cell efficacy in T-ALL by preventing T cell exhaustion via suppression of the EGR1/DUSP2 pathway, improving anti-leukemic activity and persistence.
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How Milk Sugar Fuels Immune Cells to Fight Cancer: The Surprising Role of Galactose
Posted inAllergy & Immunology Family Medicine & Nutrition news Oncology

How Milk Sugar Fuels Immune Cells to Fight Cancer: The Surprising Role of Galactose

Posted by MedXY By MedXY 11/01/2025
New research reveals that galactose from dietary sources like milk reprograms liver metabolism, boosting immune T cell activity to combat tumors by preventing their exhaustion.
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