retinitis pigmentosa

Distinct Molecular and Clinical Profiles of USH2A-Associated Retinitis Pigmentosa in Korean Patients: Implications for Targeted Therapy

By MedXY 09/19/2026

This study elucidates the unique East Asian-specific genetic variants and clinical progression of USH2A-associated retinitis pigmentosa in Koreans, highlighting the potential for exon 13-targeted treatments.

news Ophthalmology

Novel Peripheral Retinal Vascular Biomarker on Ultra-Widefield OCTA Enables Severity Grading in Retinitis Pigmentosa

By MedXY 08/24/2026

Ultra-widefield OCT angiography identifies distinct peripheral retinal vascular phenotypes and a quantitative CNZ biomarker, facilitating an objective four-stage grading system for retinitis pigmentosa severity assessment and clinical trial stratification.

news Ophthalmology

Breakthrough Optogenetic Therapy UGX-201 Shows Promise for Advanced Retinitis Pigmentosa

By MedXY 07/02/2026

An exploratory trial of UGX-201, a novel optogenetic therapy, demonstrated safety and meaningful visual improvements in patients with advanced nonsyndromic retinitis pigmentosa, including restoration of light perception in those previously without vision.

news Ophthalmology Otorhinolaryngology

Clinical Findings and Molecular Genetics of USH1C-Associated Usher Syndrome: A Retrospective Case Series

By MedXY 11/27/2025

This case series reviews clinical features, genetic variants, visual outcomes, and psychosocial impact in 28 patients with USH1C-associated Usher syndrome, highlighting slow retinal degeneration and significant social burden.