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Psychosocial Stress

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Unpacking the ‘Weathering’ Hypothesis: How Cumulative Lifespan Stress and Inflammation Drive Racial Disparities in Mortality
Posted innews Psychiatry Public Health

Unpacking the ‘Weathering’ Hypothesis: How Cumulative Lifespan Stress and Inflammation Drive Racial Disparities in Mortality

Posted by MedXY By MedXY 02/10/2026
A longitudinal study identifies that cumulative lifetime stress and systemic inflammation mediate nearly 50% of the mortality gap between Black and White adults, providing a biological link between structural inequity and premature death.
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