prophylactic antibiotics

Identifying Key Risk Factors for Perineal Wound Complications After Second-Degree Tears and Episiotomy: Insights from the REPAIR Study

By MedXY 09/17/2026

This secondary analysis of the REPAIR study identifies prolonged active second stage labor, deep tears, and physician involvement in suturing as risk factors for perineal wound complications, while prophylactic antibiotics reduce this risk.

news Oncology

Prophylactic Antibiotics Did Not Significantly Reduce Infection After Vulvar Surgery, Cohort Study Finds

By MedXY 04/20/2026

In a prospective cohort of 172 vulvar surgery patients, prophylactic antibiotics were not associated with fewer postoperative infections or complications, supporting the need for a randomized trial.

Cardiology Infectious Diseases news

Prophylactic Strategies to Prevent Infection in Lower Limb Peripheral Arterial Reconstruction: Evidence and Clinical Implications

By MedXY 12/17/2025

Cochrane review shows prophylactic antibiotics may reduce SSI risk in peripheral arterial reconstruction; closed incision negative pressure therapy offers possible benefit but evidence is low.

Infectious Diseases news OB/GYN & Women's Health

Prophylactic Antibiotics in Episiotomy and Second Degree Tears: Insights from the REPAIR Trial

By MedXY 10/31/2025

The REPAIR study demonstrates that prophylactic antibiotics reduce clinically relevant wound complications after episiotomy or second degree tears, highlighting a potential role for antibiotics in postpartum care.

Clinical Updates news

Assessing the Value of Preoperative Antibiotics in Uncomplicated Acute Appendicitis: Insights from the PERFECT-Antibiotics Trial

By MedXY 09/28/2025

Preoperative antibiotics in uncomplicated acute appendicitis do not reduce appendiceal perforation risk but lower surgical site infections. This large multicenter trial clarifies their limited role while awaiting timely appendectomy.