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pediatric HIV

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Dolutegravir and Metabolic Health in Children: Five-Year Insights from the ODYSSEY Trial
Posted innews Pediatrics

Dolutegravir and Metabolic Health in Children: Five-Year Insights from the ODYSSEY Trial

Posted by MedXY By MedXY 02/14/2026
Ancillary analysis of the ODYSSEY trial demonstrates that dolutegravir-based ART is not associated with excessive weight gain or adiposity in children and adolescents compared to standard care, while offering a superior metabolic profile over five years of follow-up.
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Very Early Neonatal ART Enables ART‑Free HIV‑1 Remission in Some Children: Clinical Insights from IMPAACT P1115
Posted inHIV/AIDS news Pediatrics

Very Early Neonatal ART Enables ART‑Free HIV‑1 Remission in Some Children: Clinical Insights from IMPAACT P1115

Posted by MedXY By MedXY 11/12/2025
IMPAACT P1115 shows that initiating combination ART within 48 hours of birth can enable sustained ART‑free HIV‑1 remission for 48+ weeks in a subset of children with in‑utero infection, but careful selection, close monitoring and standardized biomarkers are essential.
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