Nicotinamide Supplementation and Primary Open-Angle Glaucoma in Patients With Ocular Hypertension: Evidence, Mechanisms, and Clinical Implications

Nicotinamide Supplementation and Primary Open-Angle Glaucoma in Patients With Ocular Hypertension: Evidence, Mechanisms, and Clinical Implications

Systemic nicotinamide supplementation is associated with reduced risk of POAG development in ocular hypertension, improved retinal function, and better quality of life, suggesting its neuroprotective potential as an adjunctive therapy in glaucoma prevention and management.