Clinical Context: Pseudoexfoliation as a Glaucoma Time Bomb
Pseudoexfoliation syndrome (PXF), characterized by abnormal extracellular material deposition in ocular tissues, affects 10-20% of adults over 60 worldwide. This study addresses critical gaps in understanding its progression to perimetric glaucoma – the stage where visual field defects become detectable. While 30-50% of PXF patients develop ocular hypertension (OHTN), the risk in normotensive PXF eyes remains poorly quantified.
