Posted inAnesthesiology Neurology news
Neuro-Immune Crosstalk: Macrophages Directly Amplify Spontaneous Activity in Damaged Human Sensory Neurons
A groundbreaking human iPSC-derived co-culture study reveals that macrophages respond to neuronal injury by adopting a pro-algesic state, directly intensifying spontaneous neuronal firing—a key driver of chronic neuropathic pain and a novel target for future analgesics.