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Multiomics

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Multiomic Profiling and Machine Learning Reveal Distinct Molecular Subtypes of Cholangiocarcinoma and Identify TNK1 as a Novel Therapeutic Target
Posted inGastroenterology news Oncology

Multiomic Profiling and Machine Learning Reveal Distinct Molecular Subtypes of Cholangiocarcinoma and Identify TNK1 as a Novel Therapeutic Target

Posted by By MedXY 08/21/2026
This study delineates three unique molecular subtypes of cholangiocarcinoma via integrated multiomic and machine learning methodologies, highlighting TNK1 kinase as a promising targeted therapy in a metabolic subtype.
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IBDome: Integrating Molecular, Histopathological, and Clinical Data to Transform Inflammatory Bowel Disease Management
Posted inGastroenterology news Pathology & Lab Medicine/Bệnh học

IBDome: Integrating Molecular, Histopathological, and Clinical Data to Transform Inflammatory Bowel Disease Management

Posted by By MedXY 07/03/2026
IBDome offers a comprehensive multiomic atlas integrating molecular, histopathological, and clinical data, advancing the understanding and precision treatment of Crohn's disease and ulcerative colitis.
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Multiomics Outperform Phenotype in Predicting Post-Diet Weight Regain and Body Composition Dynamics
Posted inDiabetes & Endocrinology Gastroenterology news

Multiomics Outperform Phenotype in Predicting Post-Diet Weight Regain and Body Composition Dynamics

Posted by By MedXY 12/31/2025
A post hoc analysis of the LEAN-TIME trial reveals that integrating gut microbiome and metabolomic data with clinical phenotypes significantly improves the prediction of weight loss and regain, offering a framework for precision weight management and personalized obesity care.
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  • Awake Integrated Microsurgical Approach for Head and Neck Free Flap Reconstruction in Frail Patients: A Safe and Resource-Efficient Alternative to General Anesthesia
  • Hospital Variation in Early Tracheostomy and Life-Sustaining Treatment Withdrawal in Severe TBI: Insights from a Nationwide Study
  • Exploring ICU Staff Perspectives on Brain Death: Insights from a Swiss Multicenter Survey
  • International Validation of Sepsis Temperature-Trajectory Subphenotypes Reveals Immune and Coagulation Profiles with Implications for Immunoglobulin Therapy
  • Enhancing Hospital Discharge Prediction with Optimized Large Language Models: A Retrospective Cohort Study
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