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Optimizing Anesthesia in Elderly NSCLC Patients: Impact of Midazolam and Dexmedetomidine Co-Administration on Hemodynamics and Stress Response
Posted inAnesthesiology General Surgery Oncology Specialties

Optimizing Anesthesia in Elderly NSCLC Patients: Impact of Midazolam and Dexmedetomidine Co-Administration on Hemodynamics and Stress Response

Posted by By MedXY 09/15/2025
Co-administering midazolam with dexmedetomidine in elderly NSCLC patients undergoing lobectomy enhances hemodynamic stability and reduces perioperative stress response, potentially improving recovery outcomes without increasing adverse events.
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Midazolam Outperforms Melatonin as Premedication for Anxiety in Children Undergoing Elective Surgery: Insights from the MAGIC Trial
Posted innews Pediatrics Psychiatry Specialties

Midazolam Outperforms Melatonin as Premedication for Anxiety in Children Undergoing Elective Surgery: Insights from the MAGIC Trial

Posted by By MedXY 09/07/2025
The MAGIC trial reveals midazolam’s superior efficacy over melatonin in reducing preoperative anxiety in children undergoing general anaesthesia, despite melatonin’s favorable safety profile. Challenges in recruitment and implications for future research are discussed.
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Inhaled Isoflurane: A Noninferior Alternative to Midazolam for Pediatric ICU Sedation
Posted inAnesthesiology Clinical Updates Critical Care news Pediatrics Specialties

Inhaled Isoflurane: A Noninferior Alternative to Midazolam for Pediatric ICU Sedation

Posted by By MedXY 07/31/2025
A multicenter phase 3 trial finds inhaled isoflurane as effective as intravenous midazolam for sedation in mechanically ventilated children, with added benefits of reduced opioid use and faster extubation.
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