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Memantine for Premature Atrial Contractions: A Phase 2 Randomized Clinical Trial

Posted inCardiology Internal Medicine news

Memantine for Premature Atrial Contractions: A Phase 2 Randomized Clinical Trial

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By MedXY 03/20/2026

This phase 2 trial demonstrates that memantine, an NMDA receptor antagonist, significantly reduces premature atrial contractions (PACs) and nonsustained atrial tachycardia burden, suggesting the cardiac glutamatergic system as a novel therapeutic target for atrial arrhythmias.

Memantine Shows Promise for Improving Social Impairment in Youths with Autism Spectrum Disorder

Posted inClinical Updates Neurology news Pediatrics Specialties

Memantine Shows Promise for Improving Social Impairment in Youths with Autism Spectrum Disorder

Posted by

By MedXY 10/01/2025

A 12-week randomized clinical trial demonstrates memantine’s efficacy and safety in improving social impairments in youths with ASD, with elevated pgACC glutamate levels serving as a predictive biomarker for treatment response.

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