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Safety Profile Favors Apixaban Over Rivaroxaban in High-Risk Patients with Atrial Fibrillation and Peripheral Artery Disease
Posted inCardiology Internal Medicine news

Safety Profile Favors Apixaban Over Rivaroxaban in High-Risk Patients with Atrial Fibrillation and Peripheral Artery Disease

Posted by MedXY By MedXY 01/05/2026
A large-scale cohort study reveals that while rivaroxaban and apixaban offer similar protection against limb events and stroke in patients with AF and PAD, rivaroxaban is associated with a 55% higher risk of major bleeding, suggesting apixaban as a safer alternative.
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Apixaban in Subclinical Atrial Fibrillation: More Major Bleeds Driven by GI Events but Not by Intracranial or Fatal Hemorrhage
Posted inCardiology news

Apixaban in Subclinical Atrial Fibrillation: More Major Bleeds Driven by GI Events but Not by Intracranial or Fatal Hemorrhage

Posted by MedXY By MedXY 11/14/2025
In ARTESiA patients with device-detected subclinical AF, apixaban reduced thromboembolism but increased major bleeding—primarily noncritical gastrointestinal events—while intracranial and fatal bleeding rates were similar to aspirin.
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