Posted innews Respiratory
Unlocking Lung Repair: Prostaglandin I2 Receptor Activation Drives Alveolar Regeneration via JUN/p53 Pathway
Activation of the prostaglandin I2 receptor (IP) enhances alveolar epithelial regeneration by promoting AT2-to-AT1 cell transdifferentiation through modulation of the JUN/p53 signaling axis, offering a promising therapeutic avenue for lung injury and fibrosis.