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Leveling the Playing Field: New Trans-Ancestry Polygenic Risk Score Transforms Type 1 Diabetes Screening
Posted inDiabetes & Endocrinology news Pediatrics

Leveling the Playing Field: New Trans-Ancestry Polygenic Risk Score Transforms Type 1 Diabetes Screening

Posted by MedXY By MedXY 03/10/2026
Researchers have developed a trans-ancestry polygenic risk score (TA-PS) that significantly improves the accuracy of type 1 diabetes prediction across diverse ethnic groups, addressing the long-standing European bias in genetic risk assessment and paving the way for more equitable global screening.
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No Added Survival Benefit from Adjuvant Chemotherapy in Older Women with Genomically High-Risk Hormone Receptor-Positive Breast Cancer: Results from the ASTER 70s Trial
Posted inClinical Updates Oncology Specialties

No Added Survival Benefit from Adjuvant Chemotherapy in Older Women with Genomically High-Risk Hormone Receptor-Positive Breast Cancer: Results from the ASTER 70s Trial

Posted by MedXY By MedXY 08/07/2025
The ASTER 70s trial found that adding chemotherapy to hormonotherapy did not improve survival but increased toxicity in women aged 70+ with high-risk ER+/HER2- breast cancer.
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  • Comparative 1-Year Outcomes of Semaglutide, Tirzepatide, and Sleeve Gastrectomy in Obese Adults with Type 2 Diabetes: Insights from Real-World Data
  • Unveiling the Phenotype of Unclassified Pulmonary Hypertension: A Hidden Spectrum of Early Heart Failure with Preserved Ejection Fraction
  • Biomarker, Functional Status, and Quality-of-Life Trajectories Before Modes of Death in Heart Failure: Post Hoc Analysis of the FINEARTS-HF Randomized Clinical Trial
  • Decoding SLC4A3 Mutations in Short QT Syndrome: Insights from hiPSC-Derived Cardiomyocytes into Ventricular Arrhythmia and Sudden Cardiac Death
  • Decade-Long Outcomes of SAPIEN 3 TAVR vs. Surgery in Intermediate-Risk Aortic Stenosis Patients
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