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FDA Approves Linzess for Pediatric IBS with Constipation: A New Hope for Children
Posted inGastroenterology news Pediatrics

FDA Approves Linzess for Pediatric IBS with Constipation: A New Hope for Children

Posted by MedXY By MedXY 11/06/2025
The FDA has approved linaclotide (Linzess) for treating irritable bowel syndrome with constipation (IBS-C) in children 7 and older, marking the first official treatment option for pediatric IBS-C.
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Gastrointestinal Burden in CHARGE Syndrome: High Prevalence of Constipation, Age-Related Patterns, and Quality‑of‑Life Impact
Posted inGastroenterology news Pediatrics

Gastrointestinal Burden in CHARGE Syndrome: High Prevalence of Constipation, Age-Related Patterns, and Quality‑of‑Life Impact

Posted by MedXY By MedXY 11/04/2025
In a cohort of 50 individuals with CHARGE syndrome, GI problems affected 64% and constipation 48%, with constipation associated with lower PedsQL GI scores and greater comorbidity; younger patients had more diverse GI issues while older patients predominantly had constipation.
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