constipation – Medxy AI

Differential Gastrointestinal Risks of Opioids in Type 2 Diabetes Patients on GLP-1RA Therapy: A Comparative Analysis

By MedXY 09/15/2026

Among type 2 diabetes patients using GLP-1 receptor agonists, oxycodone is linked to higher short-term risks of severe gastrointestinal complications compared to hydrocodone and tramadol, warranting cautious opioid selection in this population.

Gastroenterology news Pediatrics

FDA Approves Linzess for Pediatric IBS with Constipation: A New Hope for Children

By MedXY 11/06/2025

The FDA has approved linaclotide (Linzess) for treating irritable bowel syndrome with constipation (IBS-C) in children 7 and older, marking the first official treatment option for pediatric IBS-C.

Gastroenterology news Pediatrics

Gastrointestinal Burden in CHARGE Syndrome: High Prevalence of Constipation, Age-Related Patterns, and Quality‑of‑Life Impact

By MedXY 11/04/2025

In a cohort of 50 individuals with CHARGE syndrome, GI problems affected 64% and constipation 48%, with constipation associated with lower PedsQL GI scores and greater comorbidity; younger patients had more diverse GI issues while older patients predominantly had constipation.