congenital heart disease

Enhanced Outcomes with Combined Intrahepatic and Periduodenal Lymphatic Embolization in Congenital Heart Disease-associated Protein-Losing Enteropathy

By MedXY 08/28/2026

Combined intrahepatic and periduodenal lymphatic embolization significantly improves protein balance and remission duration in congenital heart disease patients with protein-losing enteropathy compared to intrahepatic embolization alone, offering a promising targeted interventional strategy.

Cardiology news

Unveiling Heart Failure with Preserved Ejection Fraction in Adults with Congenital Heart Disease: Prevalence, Characteristics, and Clinical Challenges

By MedXY 08/12/2026

This article explores the high prevalence of heart failure with preserved ejection fraction (HFpEF) in adults with congenital heart disease (ACHD), highlighting its clinical features, hospitalization burden, and under-treatment issues.

Cardiology news Respiratory

Decoding Pulmonary Arterial Hypertension in Congenital Heart Disease: Latent Class Analysis Uncovers Distinct Risk Phenotypes and Treatment Insights

By MedXY 06/25/2026

Latent class analysis of 889 adult PAH-CHD patients identified unique phenogroups with distinct survival outcomes and treatment responses, offering refined risk stratification and guiding personalized therapy.

Cardiology news Pediatrics

Disrupted MAML1 Phase Separation Emerges as a New Mechanism Linking Notch Failure to Congenital Heart Disease

By MedXY 06/05/2026

A Circulation study identifies MAML1 as a candidate congenital heart disease gene and shows that defective phase separation in endocardial cells suppresses Notch signaling, impairing endocardial-to-mesenchymal transition and causing septal and valvular malformations.

Cardiology news Radiology

Mapping the Maze: How 3D Imaging is Transforming VT Ablation in Congenital Heart Disease

By MedXY 03/03/2026

The CORECA study reveals that preprocedural 3D anatomic and substrate reconstruction from CT or MRI effectively identifies ventricular tachycardia targets in complex congenital heart disease, achieving 87.5% concordance with electroanatomical mapping and high interobserver reproducibility.

Cardiology news Pediatrics

Over 50% of Publicly Insured Children Face Neurodevelopmental Disorders Following Infant Heart Surgery

By MedXY 02/05/2026

A comprehensive study highlights that over half of publicly insured children develop neurodevelopmental disorders within five years of infant cardiac surgery. While service utilization is high, a critical gap persists between initial screening and specialized evaluations required for optimal outcomes.

Cardiology news Pediatrics

Minima Stent System Proves Safe and Effective for Vascular Stenosis in Infants: Results of the Multicenter Pivotal Trial

By MedXY 01/18/2026

A multicenter trial confirms the Minima Stent's efficacy in treating pulmonary artery stenosis and aortic coarctation in infants. With a 97.6% success rate and growth-accommodating design, it addresses a critical unmet need in pediatric interventional cardiology.

Cardiology news Psychiatry

Tailored Digital Emotion Regulation Improves Mental Health in Adults With Congenital Heart Disease: Results of a National Randomized Trial

By MedXY 12/14/2025

A 3‑arm randomized trial in 524 adults with congenital heart disease found a 4‑week tailored digital emotion‑regulation program produced moderate improvements in emotion regulation and multiple psychosocial outcomes versus usual care; a general program showed delayed, smaller benefits.

Cardiology Specialties

Fontan Circulatory Failure and Heart Transplant Survival: Insights from a Multicenter Retrospective Cohort Study

By MedXY 09/06/2025

This study identifies key Fontan circulatory failure morbidities impacting survival from heart transplant waitlisting through one year post-transplant, highlighting cyanosis and frequent hospitalizations as critical risk factors.