Clinical Diagnostics

Clinical Factors Associated With Discordant Plasma P-Tau217 and Established Alzheimer Disease Biomarkers: Implications for Diagnosis and Management

By MedXY 10/07/2026

This review synthesizes evidence on clinical and biological factors linked to discordance between plasma p-tau217 and standard AD biomarkers, highlighting implications for diagnosis, patient stratification, and future biomarker development.

Clinical Updates news

Comparative Diagnostic Performance of Global Thyroid Ultrasound Risk Stratification Systems: The Impact of Nodule Size and Lexicon Standardization

By MedXY 03/08/2026

This review synthesizes findings from a large-scale comparison of five major thyroid ultrasound risk stratification systems (RSSs), evaluating how nodule size and standardized lexicon influence sensitivity, specificity, and unnecessary biopsy rates.

Emergency Medicine Internal Medicine news

Age-Adjusted D-Dimer Cutoffs Safely Rule Out Deep Vein Thrombosis: Results from the ADJUST-DVT Trial

By MedXY 01/06/2026

The ADJUST-DVT study confirms that an age-adjusted D-dimer cutoff (age × 10 µg/L) safely increases the number of patients in whom deep vein thrombosis can be ruled out without imaging, particularly benefiting patients over 75 years of age.