cerebral small vessel disease

Basal Ganglia Perivascular Spaces: A Dual-Risk Biomarker for Ischemic Stroke and Major Bleeding in Antithrombotic Therapy

By MedXY 03/27/2026

A large-scale prospective study identifies high basal ganglia perivascular space (BGPVS) burden as a significant predictor of both major bleeding and ischemic stroke in patients on antithrombotic regimens, offering a new imaging biomarker for personalized vascular risk assessment.

Neurology news Radiology

High Basal Ganglia Perivascular Space Burden Predicts Both Ischemic Stroke and Major Bleeding in Antithrombotic Users

By MedXY 03/22/2026

A large prospective study reveals that a high burden of basal ganglia enlarged perivascular spaces (BGPVSs) significantly increases the risk of both ischemic stroke and major bleeding in patients on antithrombotic therapy, positioning BGPVS as a critical biomarker for personalized vascular risk assessment.

Neurology news Radiology

Midlife Plasma GFAP as a Long-Term Sentinel for Cerebral Small Vessel Disease: A Decadal Prospective Study

By MedXY 01/06/2026

Elevated plasma glial fibrillary acidic protein (GFAP) in middle age independently predicts the progression of cerebral small vessel disease MRI markers nearly a decade later, suggesting its potential as an early-stage prognostic biomarker for neurovascular decline.

Clinical Updates news

Enlarged Perivascular Spaces as Early Neurovascular Biomarkers in Alzheimer Disease: Integrating Serum and MRI Findings from Multicultural Cohorts

By MedXY 10/20/2025

Enlarged perivascular spaces (EPVS) correlate with serum biomarkers of neuroinflammation and amyloid pathology and associate with cognitive impairment, supporting their role as early MRI markers for Alzheimer disease (AD) vascular contributions and pathology.