CCTA – Medxy AI

Beyond Stenosis: The Prognostic Impact of Quantitative Plaque Volumetrics in Early Coronary Artery Disease

By MedXY 03/11/2026

This review synthesizes findings from a PROMISE trial substudy, revealing that quantitative coronary plaque volume and burden are independent predictors of MACE in symptomatic outpatients, even when total plaque levels are low.

Cardiology news Radiology

Beyond Stenosis: Why Quantitative Plaque Volume Is the New Frontier in Cardiovascular Risk Assessment

By MedXY 02/22/2026

A substudy of the PROMISE trial demonstrates that quantitative plaque measures on CCTA—specifically total and noncalcified plaque burden—independently predict major adverse cardiovascular events in symptomatic outpatients, offering a precision medicine approach beyond traditional clinical risk scores.

Cardiology news

Coronary CT Angiography Modestly Improves Prediction of First Coronary Events Beyond Risk Scores and CAC

By MedXY 11/10/2025

In a Swedish cohort of 24,791 adults aged 50–64, adding CCTA-derived measures of coronary atherosclerosis to pooled cohort equations and coronary artery calcium score modestly improved prediction of first coronary events over ~8 years.

Cardiology Clinical Updates news Radiology Specialties

Advancing Noninvasive Imaging in Assessing Hemodynamic Significance of Right Coronary Artery Anomalies

By MedXY 09/27/2025

This article reviews a prospective study evaluating noninvasive anatomical and functional imaging methods to determine hemodynamic significance in right anomalous aortic origin of a coronary artery (R-AAOCA), proposing a stepwise diagnostic approach to reduce invasive testing.