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Incidental DWI-Positive Lesions as Emerging Biomarkers in Cerebral Small Vessel Disease: Insights from CAA and CADASIL Cohorts
Posted inNeurology news

Incidental DWI-Positive Lesions as Emerging Biomarkers in Cerebral Small Vessel Disease: Insights from CAA and CADASIL Cohorts

Posted by By MedXY 06/28/2026
Incidental DWI-positive lesions are prevalent in cerebral amyloid angiopathy and CADASIL, showing disease-specific distributions and associations with neurodegeneration and MRI biomarkers. These findings underscore their potential role as markers of small vessel disease.
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Distinct Small Vessel Disease Phenotype Linked to Monoallelic NOTCH3 Loss-of-Function Variants: Differentiation from CADASIL and Clinical Implications
Posted inClinical Updates Neurology news Specialties

Distinct Small Vessel Disease Phenotype Linked to Monoallelic NOTCH3 Loss-of-Function Variants: Differentiation from CADASIL and Clinical Implications

Posted by By MedXY 09/04/2025
Monoallelic NOTCH3 loss-of-function variants cause a subclinical small vessel disease distinct from CADASIL, with white matter changes but lower stroke risk; cardiovascular risk factors and aging exacerbate the phenotype.
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  • Venous Drainage Integrity as a Crucial Factor in Preventing Nipple-Areolar Complex Necrosis Post Nipple-Sparing Mastectomy: Insights from Cadaveric and Clinical Studies
  • Radix High Spreader Grafts: Advancing Dorsal Nasal Framework Reconstruction with Precision and Stability
  • Perceived Inappropriateness of Intensive Care Treatment: Prevalence, Predictors, and Impact on Patient Outcomes in Dutch ICUs
  • When Well-Done Is Not the Same: Dissecting Communication Skill Assessment in Virtual versus In-Person OSCEs Among Medicine Residents
  • IDH3 as a Metabolic Checkpoint Modulating Venetoclax Resistance in AML Stem Cells
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