Exploring Low-Dose Antithymocyte Globulin Therapy in Type 1 Diabetes: Real-World Insights Using Modified Quantitative Response of C-Peptide

Exploring Low-Dose Antithymocyte Globulin Therapy in Type 1 Diabetes: Real-World Insights Using Modified Quantitative Response of C-Peptide

This article examines real-world data on low-dose antithymocyte globulin in type 1 diabetes, assessing beta-cell function via a novel C-peptide modified quantitative response (mQR). Findings suggest feasibility, safety, and potential clinical benefit in preserving endogenous insulin secretion.
Revealing Metabolic Subtypes in Gestational Diabetes Using Dynamic OGTT-Derived C-Peptide Trajectories: Implications for Personalized Risk and Management

Revealing Metabolic Subtypes in Gestational Diabetes Using Dynamic OGTT-Derived C-Peptide Trajectories: Implications for Personalized Risk and Management

Dynamic C-peptide patterns during OGTT uncover metabolic heterogeneity in GDM, identifying insulin-resistant women at risk for fetal overgrowth and normoglycemic women at risk for preeclampsia, suggesting improved stratified treatment beyond glucose-based diagnosis.