breast cancer screening

Impact of Population-Based Pathogenic Variant Testing on Risk-Based Breast Screening Recommendations

By MedXY 06/10/2026

Population-based testing for breast cancer pathogenic variants identified many women who would not have been flagged by clinical or polygenic risk models, supporting its role in risk-based screening.

AI news Radiology

AI-Supported Mammography Outperforms Standard Double Reading: Insights from the MASAI Trial

By MedXY 02/25/2026

The MASAI trial demonstrates that AI-supported mammography screening achieves higher sensitivity and non-inferior interval cancer rates compared to standard double reading, while maintaining specificity and significantly reducing radiologist workload.

Clinical Updates news

Long-term Impact of Adjunctive Ultrasonography on Advanced Breast Cancer: A Secondary Analysis of the J-START Trial

By MedXY 02/25/2026

This review analyzes the J-START trial's secondary findings, demonstrating that adjunctive ultrasonography significantly reduces the 11-year cumulative incidence of advanced breast cancer in women aged 40–49, particularly those with dense breast tissue.

news OB/GYN & Women's Health Oncology Radiology

Adjunctive Ultrasonography Reduces Advanced Breast Cancer Risk in Women Aged 40-49: Long-Term Evidence from J-START

By MedXY 02/25/2026

A prespecified secondary analysis of the J-START trial reveals that adding ultrasonography to mammography for women aged 40-49 significantly reduces the long-term cumulative incidence of advanced breast cancer, particularly in populations where dense breast tissue is prevalent.

news Oncology Radiology

Moving Beyond Birthdays: Five-Year Absolute Risk-Based Screening Outperforms Age-Based Mammography

By MedXY 02/09/2026

A CISNET modeling study demonstrates that mammography screening tailored to 5-year absolute invasive breast cancer risk reduces false-positive recalls by up to 23% while maintaining or improving mortality benefits compared to traditional age-based strategies.

news Oncology

Personalizing Breast Cancer Screening: Insights from the WISDOM Trial on Risk-Based vs Annual Mammography

By MedXY 12/17/2025

The WISDOM trial shows risk-based breast cancer screening using genetic and clinical data as a safe alternative to annual mammography, tailoring screening frequency by individual risk without increasing advanced cancer rates.

news Oncology Public Health

Boosting Mammogram Screening Rates: What Really Works for Overdue Women?

By MedXY 11/18/2025

A Singapore trial shows simple mailed reminders effectively increase overdue mammogram screenings; additional incentives or digital interventions offer no significant benefit.

news OB/GYN & Women's Health Specialties

Removing Out-of-Pocket Costs Increases Access to 3D Mammograms

By MedXY 07/29/2025

Eliminating a $45 fee for advanced breast cancer screening technology improves access and reduces health disparities, according to recent research.