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Biochemical Response

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Liver Stiffness Measurement vs. Biochemical Response in Primary Biliary Cholangitis: Predicting Liver Decompensation with Precision
Posted inGastroenterology news Pathology & Lab Medicine

Liver Stiffness Measurement vs. Biochemical Response in Primary Biliary Cholangitis: Predicting Liver Decompensation with Precision

Posted by By MedXY 10/28/2025
In primary biliary cholangitis, liver stiffness measurement (LSM) outperforms biochemical response in predicting first hepatic decompensation, emphasizing LSM's pivotal role in clinical risk stratification despite frequent discordances between these parameters.
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Obeticholic Acid Non-Response Signals Higher Clinical Risk in Primary Biliary Cholangitis
Posted inGastroenterology Internal Medicine news

Obeticholic Acid Non-Response Signals Higher Clinical Risk in Primary Biliary Cholangitis

Posted by By MedXY 10/09/2025
In primary biliary cholangitis (PBC) patients treated with obeticholic acid (OCA), biochemical non-response strongly predicts a higher risk of clinical events including liver decompensation and mortality, underscoring the need for improved therapies.
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