antifungal therapy

Timely Antifungal Therapy Initiation Is Crucial in Improving Outcomes in Candida Septic Shock

By MedXY 11/06/2026

Delayed appropriate antifungal therapy after the onset of persistent hypotension dramatically increases mortality in Candida septic shock; survival drastically improves with treatment within 2 hours.

news Ophthalmology

Clinical Impact of Contact Lens Use in Fungal Keratitis: Insights from an 8-Year Retrospective Study

By MedXY 10/28/2026

This study compares contact lens-associated and non-contact lens-associated fungal keratitis, highlighting earlier presentation and better medical therapy outcomes in contact lens users versus a more complicated course in non-users.

news Pediatrics Respiratory

Real-World Effectiveness of Oral Corticosteroids Versus Antifungals in Allergic Bronchopulmonary Aspergillosis Among Cystic Fibrosis Patients

By MedXY 10/09/2026

A large retrospective study found that oral corticosteroids for ABPA in cystic fibrosis improve lung function, while adding antifungals offers no significant additional benefit in clinical outcomes.

Dermatology Infectious Diseases news

Efficacy of Antifungal Therapies in Tinea Capitis: Insights from a Multicenter Study in China

By MedXY 08/07/2026

A multicenter prospective real-world study in China evaluated treatment outcomes of tinea capitis, highlighting itraconazole's superior efficacy over terbinafine for certain fungal strains like Microsporum canis, informing optimized antifungal strategies.

Cardiology Clinical Updates Internal Medicine news

Olorofim for Poorly Controlled Disseminated Coccidioidomycosis: Phase 2b Clinical Efficacy and Safety Insights

By MedXY 07/24/2026

This review synthesizes key findings evaluating olorofim's clinical effectiveness and safety in patients with refractory disseminated coccidioidomycosis, emphasizing its potential role amid limited treatment options.

Infectious Diseases news Respiratory

Voriconazole Not Superior to Itraconazole for Chronic Pulmonary Aspergillosis: VICTOR-CPA Trial Reaffirms Itraconazole as First-Line in India

By MedXY 11/24/2025

A randomized trial in India found no superiority of oral voriconazole over itraconazole for chronic pulmonary aspergillosis at 6 months; efficacy was similar, but voriconazole caused more adverse events.