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Adding HE4 to the IOTA ADNEX Model for Differentiating Adnexal Masses: A Danish Prospective Multicenter Study
Posted innews OB/GYN & Women’s Health

Adding HE4 to the IOTA ADNEX Model for Differentiating Adnexal Masses: A Danish Prospective Multicenter Study

Posted by MedXY By MedXY 05/18/2026
A Danish multicenter study found that adding HE4 to the IOTA ADNEX model offered only limited, threshold-dependent benefit for assessing adnexal masses, with no meaningful improvement in non-tertiary centers.
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