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acute appendicitis

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Antibiotics vs. Surgery for Uncomplicated Appendicitis: 10-Year APPAC Trial Results Confirm Long-Term Viability
Posted inGeneral Surgery Infectious Diseases news

Antibiotics vs. Surgery for Uncomplicated Appendicitis: 10-Year APPAC Trial Results Confirm Long-Term Viability

Posted by MedXY By MedXY 01/25/2026
The 10-year follow-up of the APPAC trial demonstrates that antibiotic therapy remains a safe and effective alternative to appendectomy for uncomplicated acute appendicitis, with over 60% of patients successfully avoiding surgery for a decade.
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Assessing the Value of Preoperative Antibiotics in Uncomplicated Acute Appendicitis: Insights from the PERFECT-Antibiotics Trial
Posted inClinical Updates news

Assessing the Value of Preoperative Antibiotics in Uncomplicated Acute Appendicitis: Insights from the PERFECT-Antibiotics Trial

Posted by MedXY By MedXY 09/28/2025
Preoperative antibiotics in uncomplicated acute appendicitis do not reduce appendiceal perforation risk but lower surgical site infections. This large multicenter trial clarifies their limited role while awaiting timely appendectomy.
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