Human versus Analogue Insulin for Youth with Type 1 Diabetes in Low-Resource Settings: Insights from the HumAn-1 Trial and Complementary Evidence

Human versus Analogue Insulin for Youth with Type 1 Diabetes in Low-Resource Settings: Insights from the HumAn-1 Trial and Complementary Evidence

The HumAn-1 trial found no significant differences between insulin glargine and human isophane insulin in hypoglycemia risk or glucose control in young T1D patients in low-resource settings, underscoring accessibility over insulin type in these contexts.
Efficacy and Safety of Mirtazapine in Treating Methamphetamine Use Disorder: Insights from a Phase 3 Randomized Clinical Trial

Efficacy and Safety of Mirtazapine in Treating Methamphetamine Use Disorder: Insights from a Phase 3 Randomized Clinical Trial

This randomized clinical trial evaluated mirtazapine's safety and efficacy for methamphetamine use disorder, revealing a modest but statistically significant reduction in methamphetamine use without unexpected adverse events, offering a promising pharmacotherapy option for this challenging condition.