Efficacy and Safety of Mirtazapine in Treating Methamphetamine Use Disorder: Insights from a Phase 3 Randomized Clinical Trial

Efficacy and Safety of Mirtazapine in Treating Methamphetamine Use Disorder: Insights from a Phase 3 Randomized Clinical Trial

This randomized clinical trial evaluated mirtazapine's safety and efficacy for methamphetamine use disorder, revealing a modest but statistically significant reduction in methamphetamine use without unexpected adverse events, offering a promising pharmacotherapy option for this challenging condition.
Disparities in Postpartum Permanent Contraception Requests and Fulfillment: A Comparative Review Between Incarcerated and Community Populations

Disparities in Postpartum Permanent Contraception Requests and Fulfillment: A Comparative Review Between Incarcerated and Community Populations

This review synthesizes evidence on the lower prevalence and fulfillment rates of postpartum permanent contraception requests among incarcerated individuals compared to community counterparts, underscoring reproductive justice and health equity challenges.
Impact of Fructose-Containing Beverages and Foods from Childhood to Adulthood on Hypertension Risk: Evidence from the GUTS Cohort

Impact of Fructose-Containing Beverages and Foods from Childhood to Adulthood on Hypertension Risk: Evidence from the GUTS Cohort

This prospective cohort study investigates how fructose-containing beverages and foods, including sugar-sweetened beverages, fruit juices, and whole fruits, consumed from childhood through adulthood influence hypertension risk, highlighting differential effects based on source and offering insights for public health guidance.
Pregnancy in Women With Vascular Malformations Carries High Risks of Postpartum Hemorrhage and Symptom Worsening, While Thromboembolism Clusters in Extensive Lower-Extremity Disease

Pregnancy in Women With Vascular Malformations Carries High Risks of Postpartum Hemorrhage and Symptom Worsening, While Thromboembolism Clusters in Extensive Lower-Extremity Disease

A nationwide Dutch study suggests pregnancy in women with peripheral vascular malformations is frequently complicated by symptom progression and postpartum hemorrhage, with venous thromboembolism concentrated in extensive lower-extremity malformations.