Dissecting Depression in Diabetes: Distinct Links of Somatic and Cognitive Symptoms with Inflammation and Insulin Resistance
Posted inClinical Updates Diabetes & Endocrinology Internal Medicine news Psychiatry Specialties

Dissecting Depression in Diabetes: Distinct Links of Somatic and Cognitive Symptoms with Inflammation and Insulin Resistance

New GRADE sub-study reveals that somatic symptoms of depression, not cognitive-affective symptoms, are chiefly associated with inflammation and insulin resistance in type 2 diabetes, highlighting a pathophysiological bridge for targeted interventions.
E-cigarettes versus Combination Nicotine Replacement Therapy for Smoking Cessation in Substance Use Disorder Patients: Integrative Analysis of Recent Trials and Longitudinal Patterns
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E-cigarettes versus Combination Nicotine Replacement Therapy for Smoking Cessation in Substance Use Disorder Patients: Integrative Analysis of Recent Trials and Longitudinal Patterns

Recent trials show no significant difference in smoking cessation rates between e-cigarettes and combination nicotine replacement therapy among patients discharged from inpatient substance use withdrawal services. Longitudinal analyses reveal variable abstinence trajectories in e-cigarette trials, underscoring the need for further relapse-focused research.
Comparative Analysis of Virtual Reality Therapies for Psychotic Symptoms: Auditory Hallucinations vs. Persecutory Delusions
Posted inClinical Updates news Psychiatry Specialties Superintelligence

Comparative Analysis of Virtual Reality Therapies for Psychotic Symptoms: Auditory Hallucinations vs. Persecutory Delusions

Two randomized controlled trials evaluated immersive VR therapies targeting auditory verbal hallucinations and persecutory delusions in schizophrenia and psychosis, revealing modest benefits for hallucinations but no superior effect for cognitive VR therapy in delusions.