Psychiatry – Page 10

Not All Antidepressants Are the Same: Differential Cardiometabolic and Physiological Effects from a Large Network Meta‑analysis

By MedXY 11/11/2025

A 151‑trial network meta‑analysis of 58,534 participants shows marked differences among 30 antidepressants in weight, blood pressure, heart rate, lipids, glucose and liver enzymes; findings support individualized choice and targeted baseline and follow‑up monitoring.

Gastroenterology news Psychiatry

High Burden of ARFID Symptoms in Adults with Disorders of Gut–Brain Interaction: A Population-Based Study Signals Need for Routine Screening

By MedXY 11/10/2025

A 2023 population survey of 4,002 adults in the UK and US found that positive screens for avoidant/restrictive food intake disorder (ARFID) were common among people with disorders of gut–brain interaction (DGBI) and associated with greater health burden, underweight, poorer quality of life, and higher healthcare use.

Neurology news Psychiatry

Gamma (40 Hz) Sensory Flicker Shows Promise for Insomnia but Needs Controlled Trials

By MedXY 11/09/2025

A prospective observational study of 37 adults with insomnia reports high adherence and no serious adverse events with 40 Hz light–sound flicker and sleep-diary improvements in sleep onset, arousals, and total sleep time; limitations include lack of control, objective measures, and small sample.

Internal Medicine news Psychiatry Rehabilitation Medicine

How Much Aerobic Exercise Is Enough to Reduce Depression in Patients with Chronic Illness? A Dose–Response Meta-analysis Points to an Achievable Target

By MedXY 11/08/2025

A meta-analysis of 36 RCTs (n=2,500) found aerobic exercise significantly reduces depressive symptoms in people with chronic illness (Hedges' g -0.73). A weekly dose of ≈405 MET‑min (≈120–135 min of moderate aerobic activity) reaches a minimally important symptom change.

Neurology news Psychiatry

Persistent Depressive Symptoms After MCI Strongly Predict Progression to Alzheimer’s Disease

By MedXY 11/05/2025

In an ADNI longitudinal cohort, persistently elevated depressive symptoms over 36 months after MCI diagnosis were associated with a dose‑dependent, substantially higher hazard of conversion to Alzheimer’s disease over long-term follow-up.

Neurology news Psychiatry

Depression, Anxiety and PTSD Associated With Earlier Onset of Alzheimer’s Disease: Psychiatric Burden Lowers Age at Symptom Onset

By MedXY 11/04/2025

In two large Alzheimer cohorts, a history of depression, anxiety, or PTSD and an increased number of psychiatric comorbidities were associated with earlier age at AD symptom onset by up to ~7–8 years for multi-morbidity.

Neurology news Psychiatry

Circadian Dysregulation and Executive Dysfunction in Wolfram Syndrome: Toward Chrono‑Diagnosis and Chronotherapy

By MedXY 11/04/2025

Emerging evidence links WFS1-driven ER stress to serotonergic/cholinergic disruption, executive dysfunction, and circadian dysregulation in Wolfram syndrome. This article synthesizes recent data, outlines chrono‑informed clinical assessment, and proposes priorities for chrono‑therapeutic research.

Gastroenterology news Psychiatry

Recent Advances in Alcohol Metabolism: from the Gut to the Brain

By MedXY 11/04/2025

This article reviews the latest findings on human alcohol metabolism, covering evolutionary biology, systemic and brain-specific pathways, genetic and physiological modulators, clinical implications of metabolic variability, and emerging therapeutic targets.

news Psychiatry Public Health

SPeCIFY: Practical Guidance for Inducing and Measuring Mental Fatigue in Movement Science

By MedXY 11/04/2025

Clear, pragmatic recommendations to standardize how mental fatigue is induced, measured and reported in movement-science studies—centered on the SPeCIFY reporting checklist and multi-method assessment.

news Psychiatry Public Health

Group-Based Interventions to Reduce Gambling Involvement Among Male Football Fans

By MedXY 11/02/2025

This case report summarizes the feasibility study of a group-based gambling prevention intervention among male football fans, revealing recruitment challenges and insights into intervention delivery within football club contexts.

news Psychiatry Public Health

Understanding Sex- and Age-Specific Suicide Risk Indicators: Insights from a Large Swedish Case-Control Study

By MedXY 10/31/2025

This Swedish population-based study highlights how suicide risk indicators vary by sex and age, showing males and older adults exhibit fewer, but often higher absolute risk indicators, underscoring the need for tailored suicide prevention strategies.

news Psychiatry

Systemic Inflammation as a Modulator of Anhedonia in Major Depressive Disorder: Insights from an LPS Challenge Trial

By MedXY 10/31/2025

This RCT reveals that adults with major depressive disorder and elevated systemic inflammation exhibit heightened anhedonic responses to an inflammatory challenge, highlighting inflammation's role in depression symptomatology.

Internal Medicine news Psychiatry

Unraveling Genetic Links Between Problematic Alcohol Use and Psychiatric Disorders: Insights from Large-Scale Genomic Analyses

By MedXY 10/30/2025

This study reveals significant shared genetic architectures between problematic alcohol use and various psychiatric disorders, identifying key genes like TTC12 and ANKK1 that may underlie their comorbidity.

Neurology news Psychiatry

Cognitive Control Deficits in Specific Problematic Internet Uses: Insights From Clinically Validated Neurocognitive Assessments

By MedXY 10/30/2025

This study reveals distinct impairments in executive functions and inhibitory control across types of problematic internet use, highlighting the need for tailored interventions to address self-control deficits in internet addiction.

Neurology news Psychiatry

Polygenic Influences and Anticholinergic Burden: Unraveling Their Joint Impact on Cognition and Brain Structure in Psychosis Spectrum Disorders

By MedXY 10/30/2025

This study reveals that genetic predispositions interact with anticholinergic medication burden to influence cognitive deficits and brain gray matter volume reductions in psychosis spectrum disorders, offering new insights into personalized treatment strategies.

Neurology news Psychiatry

Cognition-Guided EEG Neurofeedback Enhances Response Inhibition in Methamphetamine Use Disorder: A Promising Neuromodulation Approach

By MedXY 10/30/2025

Cognition-guided EEG neurofeedback targeting methamphetamine cue-related brain activity significantly improves response inhibition in men with methamphetamine use disorder, surpassing standard rehabilitation outcomes and offering a novel intervention avenue.

news Psychiatry Public Health

Telehealth Prescribing of ADHD Stimulants: Assessing Risks for Subsequent Substance Use Disorders

By MedXY 10/30/2025

This study evaluates whether initiating ADHD stimulant prescriptions via telehealth affects later risks of stimulant or other substance use disorders, finding no SUD risk increase but a potential rise in stimulant use disorder risk.

news Pediatrics Psychiatry

Unveiling the Impact of Copy Number Variants on Child Psychopathology and Cognitive Development: Insights from the ABCD Study

By MedXY 10/30/2025

This study elucidates how copy number variants (CNVs) contribute to variability in child psychopathology and cognitive function, highlighting specific CNV regions and aggregated genetic risk affecting attention and cognitive domains during late childhood.

news Psychiatry

Treatment Retention in Opioid Use Disorder During Pregnancy: Buprenorphine vs Methadone Discontinuation Patterns

By MedXY 10/30/2025

This nationwide cohort study reveals higher discontinuation rates of buprenorphine than methadone during pregnancy and up to one year postpartum, highlighting significant challenges in treatment retention for opioid use disorder in pregnant patients.

Neurology news Psychiatry

Reduced Brain Iron Linked to Striatal Hyperdopaminergia in Schizophrenia: Insights from QSM MRI and PET Imaging

By MedXY 10/30/2025

This study reveals that lower brain iron levels in the substantia nigra-ventral tegmental area are associated with elevated striatal dopamine synthesis in schizophrenia, highlighting a potential new target for therapeutic intervention.