Neurology – Page 17

Harnessing Effective Connectivity Between Cerebellum and Fronto-Temporal Regions for Objective Major Depressive Disorder Diagnosis: Insights From a Multi-Site fMRI Study

By MedXY 10/30/2025

A multi-site fMRI study demonstrates that effective connectivity patterns between the cerebellum and fronto-temporal areas accurately classify major depressive disorder with over 94% accuracy, offering a promising neuroimaging biomarker to aid clinical diagnosis.

Neurology news Psychiatry

Decoding the Genetic Complexity of Impulsivity and Its Neurodevelopmental Impact

By MedXY 10/29/2025

This study reveals the heterogeneous genetic architecture of impulsivity, uncovering diverse biological pathways linking it to neurodevelopment and psychopathology across the lifespan.

Nephrology Neurology news

Environmental and Social Injustices Elevate Dementia Risk in Older Adults with End-Stage Kidney Disease: Insights from a National Registry Study

By MedXY 10/29/2025

This national registry study reveals that older adults with end-stage kidney disease (ESKD) exposed to high fine particulate pollution and racial/ethnic segregation face significantly elevated dementia risk, highlighting critical environmental and social health disparities.

Neurology news Psychiatry

Grip Strength as an Indicator of Brain Network Integrity and Well-Being in Early Psychosis

By MedXY 10/29/2025

This study links diminished grip strength in early psychosis to altered resting-state brain connectivity within key networks, suggesting grip strength as a potential marker for neural integrity and overall well-being in psychotic disorders.

Neurology news

Evaluating Alteplase Use in Minor Ischemic Stroke: Insights from a Nationwide Chinese Registry

By MedXY 10/29/2025

A nationwide Chinese registry analysis reveals no overall benefit of intravenous alteplase in minor ischemic stroke but suggests select subgroups, especially those with disabling symptoms or higher NIHSS scores, may experience improved functional outcomes.

Neurology news

Reevaluating Intravenous Tenecteplase in Minor Disabling Stroke: Insights from the TEMPO-2 Secondary Analysis

By MedXY 10/29/2025

A secondary analysis of the TEMPO-2 trial shows that intravenous tenecteplase does not improve 90-day outcomes in minor disabling stroke defined by NIHSS scores, highlighting the need to reconsider thrombolysis in this patient population.

Cardiology Neurology news

Apixaban Versus Aspirin for Recurrent Stroke Prevention in Patients with Left Ventricular Dysfunction: Insights from a Secondary Analysis of the ARCADIA Trial

By MedXY 10/29/2025

A secondary analysis of the ARCADIA trial reveals that apixaban significantly reduces recurrent ischemic stroke risk compared to aspirin in patients with left ventricular systolic dysfunction post-cryptogenic stroke.

Internal Medicine Neurology news

Emerging Role of GLP-1 and GIP/GLP-1 Receptor Agonists in Managing Idiopathic Intracranial Hypertension

By MedXY 10/27/2025

This review analyzes current evidence supporting the use of GLP-1 and GIP/GLP-1 receptor agonists in IIH, highlighting benefits in reducing papilledema, visual disturbances, and headaches.

Clinical Updates Neurology news

GLP-1 Receptor Agonists in Idiopathic Intracranial Hypertension: Emerging Evidence and Clinical Implications

By MedXY 10/27/2025

GLP-1 receptor agonists show promise in idiopathic intracranial hypertension by reducing symptoms, medication use, surgical interventions, and mortality, independent of significant BMI change, highlighting a novel therapeutic approach warranting further prospective evaluation.

Neurology news Psychiatry

Unlocking the Predictive Power of Plasma Biomarkers for Early Alzheimer’s Disease Detection

By MedXY 10/27/2025

This review evaluates recent evidence on plasma AD biomarkers, especially phosphorylated tau217 and amyloid PET, for predicting cognitive decline in unimpaired individuals, highlighting their potential and limitations.

Critical Care Neurology news

Evaluating CT Perfusion and Angiography as Ancillary Tests for Brain Death Diagnosis: Insights from a Multicenter Canadian Study

By MedXY 10/27/2025

A large Canadian prospective study assessed brain CT perfusion and angiography for confirming death by neurologic criteria, highlighting high sensitivity but suboptimal specificity, emphasizing cautious use alongside clinical examination.

Neurology news Psychiatry

Regional Specificity of Layer 3 Dendritic Spine Deficits in Schizophrenia: Implications for Cortical Circuit Dysfunction

By MedXY 10/27/2025

This study reveals region- and size-specific dendritic spine deficits in cortical layer 3 neurons of schizophrenia patients, highlighting differential synaptic disruptions across visual and prefrontal cortical areas underpinning cognitive deficits.

Cardiology Neurology Orthopedics

Long-Term Outcomes of Extracranial Vertebral Artery Reconstruction in Managing Symptomatic Vertebral Artery In-Stent Restenosis or Occlusion

By MedXY 10/24/2025

This study evaluates the efficacy of vertebral artery reconstruction surgery versus medical therapy in reducing stroke recurrence and improving neurological outcomes over a ten-year period.

Neurology Public Health Rehabilitation Medicine

Long-Term Unmet Needs and Rehabilitation Gaps: Impacts on Stroke Survivors’ Quality of Life in Korea

By MedXY 10/24/2025

This study highlights how long-term unmet needs and rehabilitation deficits adversely affect the quality of life among stroke survivors in South Korea, emphasizing the need for community-based support systems.

Neurology Public Health Rehabilitation Medicine

Addressing Disparities in Post-Stroke Community Rehabilitation: Insights from the COMPASS Study

By MedXY 10/24/2025

This article analyzes recent findings on sociodemographic and geographic disparities in community-based stroke rehabilitation from the COMPASS trial.

Neurology news Rehabilitation Medicine

Electroacupuncture in Ischemic Stroke: Integrating Preclinical Evidence into Clinical Potential

By MedXY 10/23/2025

This review synthesizes preclinical evidence on electroacupuncture's mechanisms in ischemic stroke, highlighting its therapeutic potential and factors influencing efficacy.

Neurology news

Long-Term Seizure Outcomes and Epilepsy Risk in Anti-LGI1 Encephalitis: Insights from a Multicenter Cohort Study

By MedXY 10/23/2025

This study assesses seizure remission and epilepsy risk in 236 anti-LGI1 encephalitis patients, highlighting immunotherapy's role in seizure control and identifying biomarkers linked to persistent cognitive impairment and long-term outcomes.

Neurology news

Long-Term Success of Satralizumab in Managing NMOSD: Insights from the SAkuraMoon Study

By MedXY 10/23/2025

This article reviews the long-term safety and efficacy of satralizumab in neuromyelitis optica spectrum disorder based on the SAkuraMoon extension trial.

Neurology news

ESCAPE-NEXT Trial: Nerinetide Fails to Improve Functional Outcomes in Acute Ischaemic Stroke Patients Undergoing Endovascular Thrombectomy Without Prior Thrombolysis

By MedXY 10/22/2025

The ESCAPE-NEXT trial evaluated nerinetide for acute ischaemic stroke patients undergoing thrombectomy without prior thrombolysis. Nerinetide showed no significant improvement in functional outcomes or safety concerns, highlighting the need for further research into optimal patient selection and treatment timing.