Is Single-Test Tuberculosis Screening Adequate Before Initiating Biologic Therapy?

Highlight

– Pretreatment screening with QuantiFERON-TB (QFT) Gold alone significantly reduced TB infection diagnoses and preventive therapy prescriptions compared to dual testing.
– Incident TB during biologic therapy remained low (0.8%), with most cases occurring within the first two years of treatment.
– Routine periodic TB retesting after a negative baseline screen appears unnecessary in the absence of new exposures.

Study Background and Disease Burden

1 Comment

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