Highlights
- Large multicenter TORPIDO 30/60 trial found no difference in death or brain injury between initial FiO2 of 0.6 and 0.3 in extremely preterm infants.
- Individual participant data meta-analysis suggests high initial FiO2 (≥0.90) may reduce mortality, though certainty is low.
- Deferred cord clamping with 100% oxygen reduced early hypoxemia without increasing morbidity.
Background
