Primary Sclerosing Cholangitis in a 45-Year-Old Male: A Case Report

Patient Information

A 45-year-old Caucasian male presented to the hepatology clinic with complaints of progressive pruritus and fatigue over the past three months. He reported intermittent right upper quadrant discomfort but denied jaundice or weight loss. Past medical history was notable for ulcerative colitis diagnosed five years prior, currently in clinical remission on mesalamine. There was no history of alcohol abuse or viral hepatitis risk factors. Family history was negative for liver disease.

On physical examination, the patient appeared well, without scleral icterus or hepatosplenomegaly. Dermatological examination revealed excoriations consistent with scratching due to pruritus.

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