Highlight
– Prenatal exposure to phthalates and bisphenol A (BPA), ubiquitous endocrine-disrupting chemicals, may influence the development of hypomineralized second primary molars (HSPM) in children.
– The study found sex-specific associations: higher BPA and phthalate levels during pregnancy were linked to lower risk of HSPM in girls but a trend toward higher risk in boys.
– Mixture analyses indicated that monobenzyl phthalate (mBzBP) contributed notably to lowered HSPM odds.
– These findings underscore the importance of considering combined chemical exposures during early development for dental enamel integrity.
