Neighborhood Social Vulnerability and Racial Disparities in Schizophrenia Spectrum Disorder Prevalence: Insights from a National US Study

Highlight

  • Non-Hispanic Black and multiracial adults in the US exhibit significantly higher prevalence of schizophrenia spectrum disorders (SSDs) and psychotic symptoms compared to non-Hispanic White individuals.
  • Neighborhood social vulnerability, as measured by a composite Social Vulnerability Metric (SVM), substantially attenuates racial disparities in SSD and psychotic symptom prevalence, emphasizing social determinants’ role.
  • Despite adjustment for SVM, SSD prevalence remains significantly elevated among non-Hispanic multiracial individuals, indicating additional factors beyond neighborhood vulnerability contribute to risk.
  • Findings underscore structural racism’s influence via community-level social inequities shaping mental health disparities in severe psychotic disorders.

Study Background and Disease Burden

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