Introduction
Immune-mediated inflammatory diseases (IMIDs) are increasingly recognized as rare but significant complications in patients with myelodysplastic syndromes (MDS) and chronic myelomonocytic leukemia (CMML). Among these, systemic lupus erythematosus (LE) and cutaneous LE have been described, though often presenting with atypical clinical features and showing resistance to standard rheumatologic treatments. This case report and cohort analysis explores the distinct phenotype of lupuslike manifestations in the setting of myeloid malignancies.
