Patient Information
The study population consisted of 60 biologic-naïve pediatric patients diagnosed with Acute Severe Ulcerative Colitis (ASUC). The median age at the time of enrollment was 13.5 years, with a female predominance (61.7%). These patients were recruited across ten specialized European pediatric gastroenterology centers under the auspices of the Porto IBD Working Group of ESPGHAN. At the time of presentation, all patients were experiencing an acute exacerbation of ulcerative colitis requiring hospitalization and the initiation of intravenous corticosteroid (IVCS) therapy.
