Highlight
– Single-shot intercostal nerve block (ICNB) provides noninferior pain relief compared to thoracic epidural analgesia (TEA) after thoracoscopic anatomical lung resection.
– Continuous paravertebral block (PVB) was inferior to TEA in pain control but both PVB and ICNB reduced opioid consumption and enhanced postoperative mobility.
– ICNB was associated with shorter hospital stays without increased complication rates.
– Quality of recovery scores were similar among TEA, PVB, and ICNB groups, supporting ICNB as a practical alternative for enhanced recovery protocols.
