Highlight
– The 7-year cumulative implant survival rate for fixed full-arch rehabilitation using All-on-4® implants was 91.9%.
– Bone grafting emerged as an independent risk factor for implant failure prior to definitive prosthesis placement.
– After definitive restoration, fewer implants, opposing natural teeth or fixed prostheses, and absence of night guard significantly increased implant failure risk.
– A nomogram integrating six predictors demonstrated moderate accuracy (AUC = 0.787) for predicting implant failure across treatment stages.
