Electronic Patient-Reported Outcome Monitoring With Alert-Based Interventions in Metastatic Breast Cancer: A Review of Evidence and Clinical Implications

Highlights

• Digital patient-reported outcome (PRO) monitoring with alert-based clinical responses significantly reduces fatigue in patients with metastatic breast cancer (mBC).
• Weekly electronic PRO assessments enable timely identification and intervention on symptom deterioration, leading to improved physical functioning.
• Use of standardized item banks and computerized adaptive testing optimizes PRO measurement precision and clinical actionability.
• This approach supports integration of patient-centered symptom monitoring into routine oncology care to enhance quality of life and functional status.